Überfunktion der Schilddrüse (Hyperthyreose)

Hyperthyroidism is a condition in which the thyroid gland produces excessive amounts of the thyroid hormones (T3 and T4).

 

Latent hyperthyroidism

Latent hyperthyroidism is discovered through laboratory testing which shows, at the same time, reduced TSH and normal T3 and T4 levels. With latent hyperthyroidism, the symptoms or complaints are minimal.

 

Manifest hyperthyroidism

Manifest hyperthyroidism is discovered through laboratory testing showing simultaneous low TSH and high T3 and T4 levels.  With manifest hyperthyroidism, the symptoms or complaints are more pronounced and impair the patient’s sense of well-being. 

 

 

TSH

T3

T4

Euthyroidism

normal

normal

normal

Latent hyperthyroidism

low

normal

normal

Manifest hyperthyroidism

low

low

Low

 

The symptoms of a hyperactive thyroid are both physical and psychological.

 

The most common physical complaints with a hyperactive thyroid are:

  • Rapid heartbeat
  • Weight loss
  • High blood pressure
  • Insomnia
  • Hypersensitivity to heat
  • Hair loss
  • Hand tremor
  • Muscle weakness
  • Increased frequency of bowel movements
  • Changes in the skin and nails
  • Increased sweating
  • Menstrual cycle disturbance and infertility in women
  • Calcium loss and the risk of more rapid development of osteoporosis
  • Endocrine orbitopathy (inflammatory disease of the eye socket) with Grave’s disease

The most common psychological complaints with a hyperactive thyroid are:

  • Restlessness
  • Irritability
  • Emotional instability
  • Anxiety
  • Inability to concentrate

Therapy:

Surgical removal

Radioiodine therapy

Thyrostatic drugs such as Thiamazole, Carbimazole, Perchlorate (short-term)

Beta blockers (short-term)

Avoid large amounts of iodine